Molecular Profiles™

At Molecular Profiles our experience is used to help you understand and optimise the solid state form of your drug molecule.  Solid state development of a drug candidate is a critical and often complex part of the development process, but one which ultimately leads to the regulatory requirement for selection of the final drug form. Selection should be completed as early as possible during development to minimise costly and time-consuming delays. An unanticipated change in solid state properties can affect bioavailability, stability and processing parameters. At Molecular Profiles, we assist clients resolve this challenge by providing work packages tailored to support development milestones and timescales.

Our services typically include:

• Salt, cocrystal and polymorph screening
• Polymorph investigations
• Amorphous content and stability investigations
• Solid state stability
• Hydration / solvation
• Material developability
• Batch-to-batch comparison