Services
Biological activity and immunogenicity is affected by conformation and the aggregated state. Within most biomolecular species there is inherent instability with many potential degradation pathways which can occur at formulation or storage stages. Our services are based on providing solid state characterisation and formulation development providing efficacious and stable products.
Typical services include:
- Lyophilisation and polymer based formulation development
- Solid state analysis for optimisation of lyophilised and polymeric based products
- Solid state analysis for optimisation of colloidal, nanoparticulate and microparticulate products
- Chemical mapping and imaging to study content uniformity
- Aggregation studies
- Formulated product–tertiary and solid state structural determination
- Surface analysis and optimisation of delivery systems
- Ligand-receptor binding studies